IFIT2 antibody (N-Term)

Catalog No. ABIN2773795

Product Details anti-IFIT2 Antibody

Target: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFIT2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SENNKNSLES SLRQLKCHFT WNLMEGENSL DDFEDKVFYR TEFQNREFKA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against IFIT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IFIT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 472 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-IFIT2 antibody (ABIN2773795)

Terenzi, Hui, Merrick, Sen: "Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56." in: The Journal of biological chemistry, Vol. 281, Issue 45, pp. 34064-71, (2006) (PubMed).

Target Details for IFIT2

Target: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Alternative Name: IFIT2 (IFIT2 Products)

Background: IFIT2 belongs to the IFIT family. It contains 6 TPR repeats. IFIT2 inhibits migration activity and increases survival of oral squamous cell carcinoma.
Alias Symbols: G10P2, GARG-39, IFI-54, IFI54, ISG-54K, ISG54, cig42, IFIT-2, IFI-54K, ISG-54 K
Protein Interaction Partner: NUTM1, UBC, IFIT3, TUBB, TOE1, PABPC1, DNAJA2, PABPC4, YBX3, SNRPF, SNRPE, SNRPD3, SNRPD2, SNRPD1, SNRPC, SNRPB2, SNRPB, SNRPA1, SNRPA, SNRNP70, RPLP1, RPL31, RCN2, YBX1, ILF3, ILF2, IFIT1, HNRNPL, HNRNPD, HNRNPAB, HNRNPA2B1, HNRNPA1, DBT, HNRNPDL, MATR3,
Protein Size: 472

Molecular Weight: 55 kDa

Gene ID: 3433

NCBI Accession: NM_001547, NP_001538

UniProt: P09913