RANBP1 antibody (C-Term)

Catalog No. ABIN2773873

The Rabbit Polyclonal anti-RANBP1 antibody has been validated for WB. It is suitable to detect RANBP1 in samples from Human, Cow, Horse and Saccharomyces cerevisiae.

Quick Overview for RANBP1 antibody (C-Term) (ABIN2773873)

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Reactivity: Human, Cow, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RANBP1 Antibody

Binding Specificity: C-Term

Sequence: KFEECRKEIE EREKKAGSGK NDHAEKVAEK LEALSVKEET KEDAEEKQ

Predicted Reactivity: Cow: 79%, Horse: 79%, Human: 100%, Yeast: 90%

Characteristics: This is a rabbit polyclonal antibody against RANBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RANBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 201 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RANBP1

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Alternative Name: RANBP1

Background: Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC88701, HTF9A
Protein Interaction Partner: UBC, SUMO1, MDM2, CHMP4A, PLS3, IDH1, DCK, EGFR, PTMA, RAN, rna1, XPO1, vpu, VCAM1, FN1, CFTR, HNF1A, KPNB1, RCC1, C18orf8, UBD, ELAVL1, Ranbp2, RANGRF, CD93, MPG,
Protein Size: 201

Molecular Weight: 23 kDa

Gene ID: 5902

NCBI Accession: NM_002882, NP_002873

UniProt: P43487