ABCB1 antibody (Middle Region)

Catalog No. ABIN2773986

Product Details anti-ABCB1 Antibody

Target: ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Zebrafish (Danio rerio), Sheep, Pig, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AIVPIIAIAG VVEMKMLSGQ ALKDKKELEG SGKIATEAIE NFRTVVSLTQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ABCB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ABCB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1280 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABCB1

Target: ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Alternative Name: ABCB1 (ABCB1 Products)

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct
Alias Symbols: ABC20, CD243, CLCS, GP170, MDR1, MGC163296, P-gp, PGY1, P-GP
Protein Interaction Partner: FBXO15, UBA7, UBC, MAPKAP1, BCCIP, CD4, LNX1, PSMB8, PIM1, DHX9, HAX1, RNF2, CAV1,
Protein Size: 1280

Molecular Weight: 141 kDa

Gene ID: 5243

NCBI Accession: NM_000927, NP_000918

UniProt: P08183