GABARAPL1 antibody (Middle Region)

Catalog No. ABIN2774240

The Rabbit Polyclonal anti-GABARAPL1 antibody has been validated for WB. It is suitable to detect GABARAPL1 in samples from Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) and Pig.

Quick Overview for GABARAPL1 antibody (Middle Region) (ABIN2774240)

Target: GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABARAPL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABARAPL1 Antibody

Binding Specificity: Middle Region

Sequence: VIVEKAPKAR VPDLDKRKYL VPSDLTVGQF YFLIRKRIHL RPEDALFFFV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GABARAPL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human GABARAPL1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABARAPL1

Target: GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))

Alternative Name: GABARAPL1

Background: GABARAPL1 is a Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. it is involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Protein Interaction Partner: SQSTM1, KRTAP10-3, KRTAP10-9, KRTAP10-7, FAM134C, FUNDC1, ATG4A, AHNAK2, KBTBD7, SCYL3, TNIP1, CALCOCO2, TBC1D5, UBC, SRPK2, SRPK1, DVL2, MAPK15, STBD1, BNIP3L, ULK1, RB1CC1, ATG13, MAP1LC3A, ATG3, ATG4B, ATG7, NBR1, TBC1D16, TBC1D10A, TBC1D17, TBC1D2, TB
Protein Size: 146

Molecular Weight: 16 kDa

Gene ID: 23710

Pathways: Autophagy