CD1b antibody (N-Term)

Catalog No. ABIN2774371

The Rabbit Polyclonal anti-CD1b antibody has been validated for WB. It is suitable to detect CD1b in samples from Human, Guinea Pig, Cow, Dog, Horse and Sheep.

Quick Overview for CD1b antibody (N-Term) (ABIN2774371)

Target: CD1b (CD1B)

Reactivity: Human, Guinea Pig, Cow, Dog, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1b antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD1b Antibody

Binding Specificity: N-Term

Sequence: TAIFLKPWSK GNFSDKEVAE LEEIFRVYIF GFAREVQDFA GDFQMKYPFE

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 83%, Horse: 86%, Human: 100%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against CD1B. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 333 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD1b

Target: CD1b (CD1B)

Alternative Name: CD1B

Background: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
Alias Symbols: CD1, CD1A, MGC125990, MGC125991, R1
Protein Interaction Partner: UBC, PSAP, B2M,
Protein Size: 333

Molecular Weight: 37 kDa

Gene ID: 910

NCBI Accession: NM_001764, NP_001755

UniProt: P29016