ATP6V0D1 antibody (C-Term)

Catalog No. ABIN2774453

This anti-ATP6V0D1 antibody is a Rabbit Polyclonal antibody detecting ATP6V0D1 in WB. Suitable for Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Dog, Horse and Saccharomyces cerevisiae.

Quick Overview for ATP6V0D1 antibody (C-Term) (ABIN2774453)

Target: ATP6V0D1 (ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D1 (ATP6V0D1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Dog, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V0D1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATP6V0D1 Antibody

Binding Specificity: C-Term

Sequence: GGTTADAMCP ILEFEADRRA FIITINSFGT ELSKEDRAKL FPHCGRLYPE

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ATP6V0D1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ATP6V0D1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 351 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP6V0D1

Target: ATP6V0D1 (ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D1 (ATP6V0D1))

Alternative Name: ATP6V0D1

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously.
Alias Symbols: ATP6D, ATP6DV, FLJ43534, P39, VATX, VMA6, VPATPD
Protein Interaction Partner: UBC, STAU1, RPA3, RPA2, RPA1, LIG4, ERC1, ATP6V1B1, ATXN1,
Protein Size: 351

Molecular Weight: 39 kDa

Gene ID: 9114

NCBI Accession: NM_004691, NP_004682

UniProt: P61421

Pathways: Transition Metal Ion Homeostasis, Proton Transport, ER-Nucleus Signaling, Unfolded Protein Response