CACNB1 antibody (C-Term)

Catalog No. ABIN2774675

This Rabbit Polyclonal antibody specifically detects CACNB1 in WB. It exhibits reactivity toward Human, Mouse, Cow, Guinea Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for CACNB1 antibody (C-Term) (ABIN2774675)

Target: CACNB1 (Calcium Channel, Voltage-Dependent, beta 1 Subunit (CACNB1))

Reactivity: Human, Mouse, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CACNB1 Antibody

Binding Specificity: C-Term

Sequence: RTMATAALAA SPAPVSNLQV QVLTSLRRNL GFWGGLESSQ RGSVVPQEQE

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CACNB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CACNB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 523 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CACNB1

Target: CACNB1 (Calcium Channel, Voltage-Dependent, beta 1 Subunit (CACNB1))

Alternative Name: CACNB1

Background: CACNB1 belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Alias Symbols: CAB1, CACNLB1, CCHLB1, MGC41896
Protein Interaction Partner: SRPK1, APP, ATN1, NEDD4L, UBC, REM1, DYNLL1, CACNA1A,
Protein Size: 523

Molecular Weight: 58 kDa

Gene ID: 782

NCBI Accession: NM_199247, NP_954855

UniProt: Q02641