Ube2t antibody (N-Term)
Quick Overview for Ube2t antibody (N-Term) (ABIN2774711)
Target
See all Ube2t AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- MQRASRLKRE LHMLATEPPP GITCWQDKDQ MDDLRAQILG GANTPYEKGV
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Predicted Reactivity
- Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
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Characteristics
- This is a rabbit polyclonal antibody against UBE2T. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2T
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 197 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
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Alternative Name
- UBE2T
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Background
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The covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3) (Machida et al., 2006 [PubMed 16916645]).
Alias Symbols: HSPC150, PIG50
Protein Interaction Partner: UBC, UBE2T, FANCL, UBA6, UBA1, UBE2M, SORBS3, SRA1, SUMO2, BRCA1, RNF144B, LNX2, RNF128, MARCH5, MGRN1, ARIH2, PCGF2, RNF4, TRIM27, AMFR,
Protein Size: 197 -
Molecular Weight
- 22 kDa
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Gene ID
- 29089
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NCBI Accession
- NM_014176, NP_054895
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UniProt
- Q9NPD8
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Pathways
- Chromatin Binding
Target
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