Ube2t antibody (N-Term)

Catalog No. ABIN2774711

Product Details anti-Ube2t Antibody

Target: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ube2t antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MQRASRLKRE LHMLATEPPP GITCWQDKDQ MDDLRAQILG GANTPYEKGV

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against UBE2T. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2T

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 197 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Ube2t

Target: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Alternative Name: UBE2T (Ube2t Products)

Background: The covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3) (Machida et al., 2006 [PubMed 16916645]).
Alias Symbols: HSPC150, PIG50
Protein Interaction Partner: UBC, UBE2T, FANCL, UBA6, UBA1, UBE2M, SORBS3, SRA1, SUMO2, BRCA1, RNF144B, LNX2, RNF128, MARCH5, MGRN1, ARIH2, PCGF2, RNF4, TRIM27, AMFR,
Protein Size: 197

Molecular Weight: 22 kDa

Gene ID: 29089

NCBI Accession: NM_014176, NP_054895

UniProt: Q9NPD8

Pathways: Chromatin Binding