FBXO21 antibody (C-Term)

Catalog No. ABIN2774726

The Rabbit Polyclonal anti-FBXO21 antibody is suitable to detect FBXO21 in samples from Human, Mouse, Rat, Dog, Rabbit, Guinea Pig and Horse. It has been validated for WB and IHC.

Quick Overview for FBXO21 antibody (C-Term) (ABIN2774726)

Target: FBXO21 (F-Box Protein 21 (FBXO21))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO21 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FBXO21 Antibody

Binding Specificity: C-Term

Sequence: YNVEPQEISH PDVGRYFSEF TGTHYIPNAE LEIRYPEDLE FVYETVQNIY

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO21. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FBXO21

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO21

Target: FBXO21 (F-Box Protein 21 (FBXO21))

Alternative Name: FBXO21

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
Protein Interaction Partner: TP53, CDKN1A, SUMO1, SMURF1, NEDD8, UBC, COPS5, COPS6, CUL1, ELAVL1, CNTNAP4, TERF2, TERF1,
Protein Size: 537

Molecular Weight: 63 kDa

Gene ID: 23014

UniProt: Q4G104