TRIM45 antibody (Middle Region)

Catalog No. ABIN2774790

The Rabbit Polyclonal anti-TRIM45 antibody has been validated for WB. It is suitable to detect TRIM45 in samples from Human, Mouse, Rat, Dog, Horse, Pig, Cow and Rabbit.

Quick Overview for TRIM45 antibody (Middle Region) (ABIN2774790)

Target: TRIM45 (Tripartite Motif Containing 45 (TRIM45))

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM45 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM45 Antibody

Binding Specificity: Middle Region

Sequence: EVDPAKCVLQ GEDLHRAREK QTASFTLLCK DAAGEIMGRG GDNVQVAVVP

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TRIM45. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM45

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 580 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM45

Target: TRIM45 (Tripartite Motif Containing 45 (TRIM45))

Alternative Name: TRIM45

Background: TRIM45 is a member of the tripartite motif family. It may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described.TRIM45 belongs to a family of tripartite motif (TRIM) proteins that play important roles in a variety of cellular functions, including cell proliferation, differentiation, development, oncogenesis, and apoptosis (Wang et al., 2004 [PubMed 15351693]).[supplied by OMIM].
Alias Symbols: FLJ13181, RNF99
Protein Interaction Partner: TRIM45, GNB2L1, UBE2B, UBE2D4, UBE2E3, UBE2E2, UBE2E1, UBE2D3, UBE2D2, UBE2D1, ELAVL1, UBC,
Protein Size: 580

Molecular Weight: 64 kDa

Gene ID: 80263

NCBI Accession: NM_025188, NP_079464

UniProt: Q9H8W5