Haptoglobin antibody (N-Term)

Catalog No. ABIN2775300

This Rabbit Polyclonal antibody specifically detects Haptoglobin in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Pig, Rabbit, Dog, Guinea Pig and Horse.

Quick Overview for Haptoglobin antibody (N-Term) (ABIN2775300)

Target: Haptoglobin (HP)

Reactivity: Human, Rat, Mouse, Pig, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Haptoglobin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Haptoglobin Antibody

Binding Specificity: N-Term

Sequence: MSALGAVIAL LLWGQLFAVD SGNDVTDIAD DGCPKPPEIA HGYVEHSVRY

Predicted Reactivity: Dog: 77%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Mouse: 92%, Pig: 85%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against HP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 406 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Haptoglobin

Target: Haptoglobin (HP)

Alternative Name: HP

Background: Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes.
Alias Symbols: hp2-alpha, BP, HPA1S, HP2ALPHA2
Protein Interaction Partner: GADD45G, LAMC3, MVP, WASL, TP63, TGM2, TBL1X, RPL11, SMAD3, ALB, VKORC1, ATP7B, ELAVL1, RBBP6, GRB2, MIS12, C1RL, CD163, ADAMTS4, ITGB2, HBB, ITGAM, CD22,
Protein Size: 406

Molecular Weight: 45 kDa

Gene ID: 3240

NCBI Accession: NM_005143, NP_005134

UniProt: P00738

Pathways: Transition Metal Ion Homeostasis