ZFP36 antibody (N-Term)

Catalog No. ABIN2775764

This Rabbit Polyclonal antibody specifically detects ZFP36 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit and Sheep and has been mentioned in 2+ publications.

Quick Overview for ZFP36 antibody (N-Term) (ABIN2775764)

Target: ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFP36 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZFP36 Antibody

Binding Specificity: N-Term

Sequence: PLAPRLGPEL SPSPTSPTAT STTPSRYKTE LCRTFSESGR CRYGAKCQFA

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against ZFP36. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZFP36

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ZFP36 antibody (ABIN2775764)

Marti, Zurfluh, Hagens, Pianezzi, Klumpp, Loessner: "Long tail fibres of the novel broad-host-range T-even bacteriophage S16 specifically recognize Salmonella OmpC." in: Molecular microbiology, Vol. 87, Issue 4, pp. 818-34, (2013) (PubMed).

Fähling, Persson, Klinger, Benko, Steege, Kasim, Patzak, Persson, Wolf, Blüthgen, Mrowka: "Multilevel regulation of HIF-1 signaling by TTP." in: Molecular biology of the cell, Vol. 23, Issue 20, pp. 4129-41, (2012) (PubMed).

Target Details for ZFP36

Target: ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))

Alternative Name: ZFP36

Background: Located on chromosome 19, ZFP36 encodes a protein that is involved in controlling pro-inflammatory cytokines.
Alias Symbols: TTP, G0S24, GOS24, TIS11, NUP475, RNF162A
Protein Interaction Partner: YWHAB, PPP2CA, DNAJB1, DCP1B, DHX36, PRR5L, XRN1, UBC, TRAF2, EXOSC6, UPF2, EXOSC8, YWHAQ, TNF, DCP2, EDC3, DCP1A, EDC4, CDK6, APP, LIN28A, SH3KBP1, PABPC1, NCL, MAP3K4, HSPA4, HDAC7, HDAC3, NFKB1, HOXC9, HDAC1, CCDC85B, MAPKAPK2, YWHAG, SFN, HMGB1, NUP21
Protein Size: 326

Molecular Weight: 34 kDa

Gene ID: 7538

NCBI Accession: NM_003407, NP_003398

UniProt: P26651