UHRF2 antibody (N-Term)

Catalog No. ABIN2776012

This anti-UHRF2 antibody is a Rabbit Polyclonal antibody detecting UHRF2 in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig. This Primary Antibody has been cited in 1 publication.

Quick Overview for UHRF2 antibody (N-Term) (ABIN2776012)

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-UHRF2 Antibody

Binding Specificity: N-Term

Sequence: TNKLDSVPST SNSDCVAADE DVIYHIQYDE YPESGTLEMN VKDLRPRART

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against UHRF2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UHRF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 802 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-UHRF2 antibody (ABIN2776012)

Liu, Zhu, Zhou, Zhang, Xu, Li: "[Analysis of diagnosis and misdiagnosis of pulmonary thromboembolism in emergency]." in: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, Vol. 16, Issue 8, pp. 464-7, (2004) (PubMed).

Target Details for UHRF2

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Alternative Name: UHRF2

Background: UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis.
Alias Symbols: NIRF, URF2, RNF107, RP11-472F14.2
Protein Interaction Partner: UBE2D1, UBC, TP53, UHRF2, TRIM27, E2F1, MPG, SMAD4, ZNF131, SUMO1, UBE2I, ATXN1, USP7, TWF2, TRIM8, RBCK1, TFAP4, PCNP, CDK2, CCNE1, UHRF1, EHMT2, HIST1H3A, SUMO2, DNMT3B, DNMT3A, DNMT1, CDK1, CD27, CCNB1, CCNA2, BCL2L1, CCND1, BAX, BCAR1, YY1, SKP1, RB1,
Protein Size: 802

Molecular Weight: 90 kDa

Gene ID: 115426

NCBI Accession: NM_152896, NP_690856

UniProt: Q96PU4