HTR3E antibody (Middle Region)

Catalog No. ABIN2776341

This Rabbit Polyclonal antibody specifically detects HTR3E in WB and IF. It exhibits reactivity toward Human, Dog, Rabbit and Horse.

Quick Overview for HTR3E antibody (Middle Region) (ABIN2776341)

Target: HTR3E (Serotonin Receptor 3E (HTR3E))

Reactivity: Human, Dog, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR3E antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-HTR3E Antibody

Binding Specificity: Middle Region

Sequence: RWLHSLLLHC NSPGRCCPTA PQKENKGPGL TPTHLPGVKE PEVSAGQMPG

Predicted Reactivity: Dog: 100%, Horse: 83%, Human: 100%, Rabbit: 83%

Characteristics: This is a rabbit polyclonal antibody against HTR3E. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HTR3E

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 471 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HTR3E

Target: HTR3E (Serotonin Receptor 3E (HTR3E))

Alternative Name: HTR3E

Background: HTR3E belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
Alias Symbols: 5-HT3c1, MGC120035, MGC120036, MGC120037, 5-HT3E, 5-HT3-E
Protein Size: 471

Molecular Weight: 53 kDa

Gene ID: 285242

NCBI Accession: NM_182589, NP_872395

UniProt: A5X5Y0