RAVER1 antibody (Middle Region)

Catalog No. ABIN2776618

This anti-RAVER1 antibody is a Rabbit Polyclonal antibody detecting RAVER1 in WB. Suitable for Human, Guinea Pig, Cow, Dog, Horse, Rabbit, Pig, Mouse and Rat.

Quick Overview for RAVER1 antibody (Middle Region) (ABIN2776618)

Target: RAVER1 (Ribonucleoprotein, PTB-Binding 1 (RAVER1))

Reactivity: Human, Guinea Pig, Cow, Dog, Horse, Rabbit, Pig, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAVER1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAVER1 Antibody

Binding Specificity: Middle Region

Sequence: ALLQLALQTQ GQKKPGILGD SPLGALQPGA QPANPLLGEL PAGGGLPPEL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against RAVER1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAVER1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 756 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAVER1

Target: RAVER1 (Ribonucleoprotein, PTB-Binding 1 (RAVER1))

Alternative Name: RAVER1

Background: RAVER1 contains 3 RRM (RNA recognition motif) domains. It cooperates with PTBP1 to modulate regulated alternative splicing events and promotes exon skipping. It cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
Alias Symbols: KIAA1978
Protein Interaction Partner: FUS, NEDD1, CEP76, CEP72, HAUS2, CEP250, AURKB, TUBG1, TP53, PPP2R1A, LGALS3BP, CDKN1A, CDC20, AIRE, STAU1, UBC, RPA3, RPA2, RPA1, WHSC1, VCAM1, FN1, MCAT, DYNLT1, SDHA, PHKB, ABCC1, AK2, ELAVL1, SUMO2, Cnot3, TERF2, PTBP1, VCL, ACTN1, ACTN2,
Protein Size: 756

Molecular Weight: 79 kDa

Gene ID: 125950

NCBI Accession: NM_133452, NP_597709

UniProt: Q8IY67