Synaptojanin 1 antibody (Middle Region)

Catalog No. ABIN502076

The Rabbit Polyclonal anti-Synaptojanin 1 antibody has been validated for WB. It is suitable to detect Synaptojanin 1 in samples from Human, Rat, Mouse, Pig, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for Synaptojanin 1 antibody (Middle Region) (ABIN502076)

Target: Synaptojanin 1 (SYNJ1)

Reactivity: Human, Rat, Mouse, Pig, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptojanin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Synaptojanin 1 Antibody

Binding Specificity: Middle Region

Sequence: PGVARREMEA PKSPGTTRKD NIGRSQPSPQ AGLAGPGPAG YSTARPTIPP

Predicted Reactivity: Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against SYNJ1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SYNJ1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1573 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Synaptojanin 1

Target: Synaptojanin 1 (SYNJ1)

Alternative Name: SYNJ1

Background: Synaptojanin 1 is a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking.
Alias Symbols: INPP5G
Protein Interaction Partner: UBC, GRB2, CLTC, CLTA, AP2M1, AP2A1, ITSN1, SH3KBP1, SH3GL1, AMPH, SH3GLB1, SORBS2, FNBP4, SH3BP1, EPS15, PACSIN3, PACSIN1, SH3GL2, SH3GL3, BIN1, EPHB2, CDK5, PPP3CA, PACSIN2,
Protein Size: 1573

Molecular Weight: 173 kDa

Gene ID: 8867

NCBI Accession: NM_003895, NP_003886

UniProt: O43426

Pathways: Inositol Metabolic Process, Synaptic Vesicle Exocytosis