MYH7 antibody (Middle Region)

Catalog No. ABIN2776777

This Rabbit Polyclonal antibody specifically detects MYH7 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio) and has been mentioned in 3+ publications.

Quick Overview for MYH7 antibody (Middle Region) (ABIN2776777)

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYH7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MYH7 Antibody

Binding Specificity: Middle Region

Sequence: TLEDQMNEHR SKAEETQRSV NDLTSQRAKL QTENGELSRQ LDEKEALISQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Myh7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1935 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MYH7 antibody (ABIN2776777)

Rouillon, Poupiot, Zocevic, Amor, Léger, Garcia, Camadro, Wong, Pinilla, Cosette, Coenen-Stass, Mcclorey, Roberts, Wood, Servais, Udd, Voit, Richard, Svinartchouk: "Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies." in: Human molecular genetics, Vol. 24, Issue 17, pp. 4916-32, (2016) (PubMed).

Tijore, Cai, Nai, Zhuyun, Yu, Tay, Lim, Chen, Tan: "Role of Cytoskeletal Tension in the Induction of Cardiomyogenic Differentiation in Micropatterned Human Mesenchymal Stem Cell." in: Advanced healthcare materials, Vol. 4, Issue 9, pp. 1399-407, (2015) (PubMed).

Tijore, Hariharan, Yu, Lam, Wen, Tay, Ahmed, Tan: "Investigating the spatial distribution of integrin β₁ in patterned human mesenchymal stem cells using super-resolution imaging." in: ACS applied materials & interfaces, Vol. 6, Issue 18, pp. 15686-96, (2014) (PubMed).

Target Details for MYH7

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Alternative Name: Myh7

Background: Myh7 play a role in muscle contraction.
Alias Symbols: Myhc-b, Myhcb, B-MHC, MyHC-I, beta-MHC
Protein Size: 1935

Molecular Weight: 223 kDa

Gene ID: 140781

NCBI Accession: NM_080728, NP_542766

UniProt: Q91Z83