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FTCD antibody (Middle Region)

This anti-FTCD antibody is a Rabbit Polyclonal antibody detecting FTCD in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig, Horse and Zebrafish (Danio rerio). This Primary Antibody has been cited in 1 publication.
Catalog No. ABIN2776888

Quick Overview for FTCD antibody (Middle Region) (ABIN2776888)

Target

See all FTCD Antibodies
FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Reactivity

  • 35
  • 13
  • 13
  • 7
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host

  • 22
  • 12
  • 4
Rabbit

Clonality

  • 20
  • 17
  • 1
Polyclonal

Conjugate

  • 30
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FTCD antibody is un-conjugated

Application

  • 30
  • 17
  • 10
  • 9
  • 9
  • 8
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Binding Specificity

    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequence

    KFLIAFNINL LGTKEQAHRI ALNLREQGRG KDQPGRLKKV QGIGWYLDEK

    Predicted Reactivity

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

    Characteristics

    This is a rabbit polyclonal antibody against FTCD. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human FTCD
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 549 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

  • Target

    FTCD (Formiminotransferase Cyclodeaminase (FTCD))

    Alternative Name

    FTCD

    Background

    FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool.[supplied by OMIM].
    Alias Symbols: LCHC1
    Protein Interaction Partner: CCDC155, MED4, TNKS2, GRB14,
    Protein Size: 549

    Molecular Weight

    59 kDa

    Gene ID

    10841

    NCBI Accession

    NM_006657, NP_006648

    UniProt

    O95954
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