BDKRB2 antibody (N-Term)

Catalog No. ABIN2776988

The Rabbit Polyclonal anti-BDKRB2 antibody has been validated for WB. It is suitable to detect BDKRB2 in samples from Human and Cow.

Quick Overview for BDKRB2 antibody (N-Term) (ABIN2776988)

Target: BDKRB2 (Bradykinin Receptor B2 (BDKRB2))

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BDKRB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BDKRB2 Antibody

Binding Specificity: N-Term

Sequence: MFSPWKISMF LSVREDSVPT TASFSADMLN VTLQGPTLNG TFAQSKCPQV

Predicted Reactivity: Cow: 77%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against BDKRB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BDKRB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 391 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BDKRB2

Target: BDKRB2 (Bradykinin Receptor B2 (BDKRB2))

Alternative Name: BDKRB2

Background: BDKRB2 is a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system.This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
Alias Symbols: B2R, BK-2, BK2, BKR2, BRB2, DKFZp686O088
Protein Interaction Partner: BAG3, ACE, GRK5, GRK6, PRKCD, PTPN11, NOS1, NOS3, GNA11, GRK4, ADRBK2, ADRBK1, AGTR1,
Protein Size: 391

Molecular Weight: 43 kDa

Gene ID: 624

NCBI Accession: NM_000623, NP_000614

UniProt: P30411

Pathways: ACE Inhibitor Pathway, Negative Regulation of intrinsic apoptotic Signaling