MAGEA10 antibody (Middle Region)

Catalog No. ABIN2777032

This Rabbit Polyclonal antibody specifically detects MAGEA10 in WB. It exhibits reactivity toward Human, Mouse, Rabbit, Rat, Cow, Dog, Guinea Pig, Horse and Pig.

Quick Overview for MAGEA10 antibody (Middle Region) (ABIN2777032)

Target: MAGEA10 (Melanoma Antigen Family A, 10 (MAGEA10))

Reactivity: Human, Mouse, Rabbit, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAGEA10 Antibody

Binding Specificity: Middle Region

Sequence: GSDPRSFPLW YEEALKDEEE RAQDRIATTD DTTAMASASS SATGSFSYPE

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 90%, Horse: 91%, Human: 100%, Mouse: 91%, Pig: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MAGEA10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAGEA10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 369 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA10

Target: MAGEA10 (Melanoma Antigen Family A, 10 (MAGEA10))

Alternative Name: MAGEA10

Background: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: MAGE10, MGC10599, CT1.10
Protein Interaction Partner: UBC,
Protein Size: 369

Molecular Weight: 41 kDa

Gene ID: 4109

NCBI Accession: NM_001011543, NP_001011543

UniProt: P43363