Glutathione Peroxidase 2 antibody (Middle Region)

Catalog No. ABIN2777110

The Rabbit Polyclonal anti-Glutathione Peroxidase 2 antibody has been validated for WB. It is suitable to detect Glutathione Peroxidase 2 in samples from Human, Mouse, Rat, Dog, Pig, Cow and Zebrafish (Danio rerio).

Quick Overview for Glutathione Peroxidase 2 antibody (Middle Region) (ABIN2777110)

Target: Glutathione Peroxidase 2 (GPX2)

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Peroxidase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glutathione Peroxidase 2 Antibody

Binding Specificity: Middle Region

Sequence: GGGYQPTFTL VQKCEVNGQN EHPVFAYLKD KLPYPYDDPF SLMTDPKLII

Predicted Reactivity: Cow: 100%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against GPX2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GPX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 190 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Glutathione Peroxidase 2

Target: Glutathione Peroxidase 2 (GPX2)

Alternative Name: GPX2

Background: This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.
Alias Symbols: GI-GPx, GPRP, GSHPX-GI, GSHPx-2, GPx-2, GPRP-2, GPx-GI
Protein Interaction Partner: TP53, PSMB2, MYC, GPX2,
Protein Size: 190

Molecular Weight: 22 kDa

Gene ID: 2877

NCBI Accession: NM_002083, NP_002074

UniProt: P18283

Pathways: Thyroid Hormone Synthesis