ESRRG antibody (Middle Region)

Catalog No. ABIN182396

The Rabbit Polyclonal anti-ESRRG antibody has been validated for WB and IHC. It is suitable to detect ESRRG in samples from Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio) and Guinea Pig. There are 2+ publications available.

Quick Overview for ESRRG antibody (Middle Region) (ABIN182396)

Target: ESRRG (Estrogen-Related Receptor gamma (ESRRG))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRRG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ESRRG Antibody

Binding Specificity: Middle Region

Sequence: RIDAENSPYL NPQLVQPAKK PYNKIVSHLL VAEPEKIYAM PDPTVPDSDI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ESRRG. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ESRRG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 458 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ESRRG antibody (ABIN182396)

Song, Wang: "A conserved gene structure and expression regulation of miR-433 and miR-127 in mammals." in: PLoS ONE, Vol. 4, Issue 11, pp. e7829, (2009) (PubMed).

Song, Wang: "Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRgamma." in: Nucleic acids research, Vol. 36, Issue 18, pp. 5727-35, (2008) (PubMed).

Target Details for ESRRG

Target: ESRRG (Estrogen-Related Receptor gamma (ESRRG))

Alternative Name: ESRRG

Background: ERRs, which are coexpressed with ERs in prostatic cells, could regulate cell growth and modulate ER-mediated pathways via interference on ERalpha transcription in prostatic cells. Not only PNRC2 but also the corepressor TLE1 functioned as ERRgamma coactivator in a reporter gene analysis. Transcriptional activation by ERR3 can be ligand-independent.
Alias Symbols: ERR3, NR3B3, ERRgamma
Protein Interaction Partner: MEOX2, KIFC3, ESRRG, NR0B1, SUMO1P1, CCDC67, KIAA1598, NUP160, SRPK1, SRA1, PPARGC1A, APP, PNRC2, NR0B2, TLE1, ESRRA, EIF3I, NRIP1, SRC, PROX1, DUT, ARHGEF15, PNRC1, EBP, UBC, PARK2, DPF2, SP1, PPARGC1B, DAXX, NCOA1, CALM1, HGS,
Protein Size: 458

Molecular Weight: 51 kDa

Gene ID: 2104

NCBI Accession: NM_206595, NP_996318

UniProt: P62508

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway