WDHD1 antibody (Middle Region)

Catalog No. ABIN2777627

This Rabbit Polyclonal antibody specifically detects WDHD1 in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Pig, Rabbit, Rat and Horse.

Quick Overview for WDHD1 antibody (Middle Region) (ABIN2777627)

Target: WDHD1 (WD Repeat and HMG-Box DNA Binding Protein 1 (WDHD1))

Reactivity: Human, Mouse, Cow, Dog, Pig, Rabbit, Rat, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDHD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WDHD1 Antibody

Binding Specificity: Middle Region

Sequence: KQILHGDPLP LTRKSYLAWI GFSAEGTPCY VDSEGIVRML NRGLGNTWTP

Specificity: Reactive with the SepB fragment (428-850aa) of WDHD1.

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against WDHD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WDHD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1129 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WDHD1

Target: WDHD1 (WD Repeat and HMG-Box DNA Binding Protein 1 (WDHD1))

Alternative Name: WDHD1

Background: WDHD1 contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. WDHD1 may also be involved in protein-protein interactions. The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: AND-1, CTF4, CHTF4
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, RABEP2, BRCC3, CD2AP, KIAA1033, SNRNP200, HNRNPR, TXNDC9, BAG6, POLR2A, MAP4, UBD, PAXIP1, ECT2, PLBD2, COA7, TRAP1, ZMYM3, SELENBP1, YY1, PLAUR, HIST2H3C, KAT2A, SUMO2, NCOA2, SRC,
Protein Size: 1129

Molecular Weight: 126 kDa

Gene ID: 11169

NCBI Accession: NM_007086, NP_009017

UniProt: O75717