PBXIP1 antibody (N-Term)
Quick Overview for PBXIP1 antibody (N-Term) (ABIN2777673)
Target
See all PBXIP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- AGGEGAGGEL GISLNMCLLG ALVLLGLGVL LFSGGLSESE TGPMEEVERQ
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Predicted Reactivity
- Cow: 92%, Human: 100%, Mouse: 92%, Rat: 86%
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Characteristics
- This is a rabbit polyclonal antibody against PBXIP1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PBXIP1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 731 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))
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Alternative Name
- PBXIP1
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Background
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PBXIP1 is the regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
Alias Symbols: HPIP
Protein Interaction Partner: MORF4L1, SGTA, GMCL1, DEF6, UBQLN1, DAXX, CCNC, UBC, SUMO1, NEDD8, RNF2, CCDC53, ZMYND8, MDFI, UBQLN4, PRKAA2, GRB2, PCBD2, ZZZ3, BRPF1, CCDC85B, DPPA2, TSNAX,
Protein Size: 731 -
Molecular Weight
- 81 kDa
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Gene ID
- 57326
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NCBI Accession
- NM_020524, NP_065385
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UniProt
- Q96AQ6
Target
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