SLC38A2 antibody (N-Term)

Catalog No. ABIN404849

The Rabbit Polyclonal anti-SLC38A2 antibody has been validated for WB. It is suitable to detect SLC38A2 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit. There are 2+ publications available.

Quick Overview for SLC38A2 antibody (N-Term) (ABIN404849)

Target: SLC38A2 (Solute Carrier Family 38, Member 2 (SLC38A2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC38A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC38A2 Antibody

Binding Specificity: N-Term

Sequence: AALKSHYADV DPENQNFLLE SNLGKKKYET EFHPGTTSFG MSVFNLSNAI

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SLC38A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC38A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 506 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC38A2 antibody (ABIN404849)

Hernandez-García, Manjarín, Suryawan, Nguyen, Davis, Orellana: "Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia." in: Pediatric research, Vol. 80, Issue 3, pp. 448-51, (2016) (PubMed).

Suryawan, Nguyen, Almonaci, Davis: "Abundance of amino acid transporters involved in mTORC1 activation in skeletal muscle of neonatal pigs is developmentally regulated." in: Amino acids, Vol. 45, Issue 3, pp. 523-30, (2013) (PubMed).

Target Details for SLC38A2

Target: SLC38A2 (Solute Carrier Family 38, Member 2 (SLC38A2))

Alternative Name: SLC38A2

Background: Under hypertonic conditions the induction of SLC38A2/SNAT2 leads to the stimulation of transport system A and to the increase in the cell content of amino acids. Its amino acid response element, along with a nearby conserved CAAT box, has enhancer activity in that it functions in an orientation and position independent manner, and it confers regulated transcription to a heterologous promoter.
Alias Symbols: ATA2, KIAA1382, PRO1068, SAT2, SNAT2
Protein Interaction Partner: UBC, APP, MCU, FLOT1, COX5A, ELAVL1, STX11,
Protein Size: 506

Molecular Weight: 56 kDa

Gene ID: 54407

NCBI Accession: NM_018976, NP_061849

UniProt: Q96QD8

Pathways: Dicarboxylic Acid Transport