MRGBP antibody (Middle Region)

Catalog No. ABIN2777883

Product Details anti-MRGBP Antibody

Target: MRGBP (MRG-Binding Protein (MRGBP))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Guinea Pig, Cow, Rat, Horse, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGBP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LSTMYDMQAL HESEILPFPN PERNFVLPEE IIQEVREGKV MIEEEMKEEM

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against C20ORF20. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C20ORF20

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 204 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRGBP

Target: MRGBP (MRG-Binding Protein (MRGBP))

Alternative Name: C20ORF20 (MRGBP Products)

Background: C20orf20 belongs to the EAF7 family. It is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Alias Symbols: Eaf7, MRGBP, URCC4, MRG15BP, C20ORF20
Protein Interaction Partner: MORF4L1, MORF4L2, NOTCH2NL, KRTAP10-7, H2AFZ, ELAVL1, SH3BP4, VAV2, UBC, H2AFV, MRFAP1, EPC1, DMAP1, MRGBP, MBTD1, EPC2, SIN3B, BRD8, RUVBL2, SRCAP, KAT5, RUVBL1, HIST2H2BE, TUBA1A, TUBB2A, RBBP7, HNRNPM, LMNA, KPNA2, KPNB1, HSPA4, HNRNPU, HNRNPK, ACTL6A,
Protein Size: 204

Molecular Weight: 22 kDa

Gene ID: 55257

NCBI Accession: NM_018270, NP_060740

UniProt: Q9NV56