FOXL2 antibody (N-Term)

Catalog No. ABIN2777885

The Rabbit Polyclonal anti-FOXL2 antibody has been validated for WB. It is suitable to detect FOXL2 in samples from Human, Mouse, Rat, Cow, Pig, Dog, Rabbit and Goat. There is 1 publication available.

Quick Overview for FOXL2 antibody (N-Term) (ABIN2777885)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Rabbit, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOXL2 Antibody

Binding Specificity: N-Term

Sequence: MMASYPEPED AAGALLAPET GRTVKEPEGP PPSPGKGGGG GGGTAPEKPD

Predicted Reactivity: Cow: 84%, Dog: 100%, Goat: 92%, Human: 100%, Mouse: 84%, Pig: 100%, Rabbit: 92%, Rat: 84%

Characteristics: This is a rabbit polyclonal antibody against FOXL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 376 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FOXL2 antibody (ABIN2777885)

Tang, Wang, Lin, Sun, Wang, Yu: "Mutation analysis of the FOXL2 gene in Chinese patients with blepharophimosis-ptosis-epicanthus inversus syndrome." in: Mutagenesis, Vol. 21, Issue 1, pp. 35-9, (2006) (PubMed).

Target Details for FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Alternative Name: FOXL2

Background: FOXL2 is a member of the forkhead family. The forkhead domain is a monomeric DNA binding motif that defines a rapidly growing family of eukaryotic transcriptional regulators. Genetic and biochemical data suggest a central role in embryonic development for forkhead proteins.
Alias Symbols: BPES, PFRK, POF3, BPES1, PINTO
Protein Interaction Partner: LATS1, SUMO1, UBE2I, ELAVL1, SMAD3, PAK1,
Protein Size: 376

Molecular Weight: 39 kDa

Gene ID: 668

NCBI Accession: NM_023067, NP_075555

UniProt: P58012

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity