T Brachyury Protein (N-Term) antibody

Catalog No. ABIN2777906

This Rabbit Polyclonal antibody specifically detects in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Rat, Guinea Pig and Rabbit.

Quick Overview for T Brachyury Protein (N-Term) antibody (ABIN2777906)

Target: T Brachyury Protein

Reactivity: Human, Mouse, Cow, Dog, Rat, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Sequence: SSPGTESAGK SLQYRVDHLL SAVENELQAG SEKGDPTERE LRVGLEESEL

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against T. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human T

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 435 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: T Brachyury Protein

Background: The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.
Alias Symbols: MGC104817, TFT
Protein Size: 435

Molecular Weight: 47 kDa

Gene ID: 6862

NCBI Accession: NM_003181, NP_003172

UniProt: O15178

Pathways: Tube Formation