TBX4 antibody (Middle Region)

Catalog No. ABIN182868

This anti-TBX4 antibody is a Rabbit Polyclonal antibody detecting TBX4 in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Rabbit, Goat, Guinea Pig, Horse, Sheep and Zebrafish (Danio rerio).

Quick Overview for TBX4 antibody (Middle Region) (ABIN182868)

Target: TBX4 (T-Box 4 (TBX4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Goat, Guinea Pig, Horse, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBX4 Antibody

Binding Specificity: Middle Region

Sequence: LRVARLQSKE YPVISKSIMR QRLISPQLSA TPDVGPLLGT HQALQHYQHE

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TBX4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 545 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TBX4

Target: TBX4 (T-Box 4 (TBX4))

Alternative Name: TBX4

Background: The TBX4 gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.
Alias Symbols: SPS
Protein Interaction Partner: FAM46A,
Protein Size: 545

Molecular Weight: 60 kDa

Gene ID: 9496

NCBI Accession: NM_018488, NP_060958

UniProt: P57082