Recoverin antibody (C-Term)

Catalog No. ABIN2778299

This Rabbit Polyclonal antibody specifically detects Recoverin in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Guinea Pig.

Quick Overview for Recoverin antibody (C-Term) (ABIN2778299)

Target: Recoverin (RCVRN)

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Recoverin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Recoverin Antibody

Binding Specificity: C-Term

Sequence: DVKLLPDDEN TPEKRAEKIW KYFGKNDDDK LTEKEFIEGT LANKEILRLI

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against RCVRN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RCVRN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 200 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Recoverin

Target: Recoverin (RCVRN)

Alternative Name: RCVRN

Background: RCVRN is a member of the recoverin family of neuronal calcium sensors. The protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.
Alias Symbols: RCV1
Protein Interaction Partner: GIT2, TGFBR2, SMAD3, IL15RA, TOP1, PQBP1, CAV1, GRK5, GRK6, GRK1, ADRBK1,
Protein Size: 200

Molecular Weight: 23 kDa

Gene ID: 5957

NCBI Accession: NM_002903, NP_002894

UniProt: P35243

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction