Recoverin antibody (N-Term)
Quick Overview for Recoverin antibody (N-Term) (ABIN2778300)
Target
See all Recoverin (RCVRN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- GNSKSGALSK EILEELQLNT KFSEEELCSW YQSFLKDCPT GRITQQQFQS
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%
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Characteristics
- This is a rabbit polyclonal antibody against RCVRN. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RCVRN
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 200 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Recoverin (RCVRN)
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Alternative Name
- RCVRN
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Background
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RCVRN is a member of the recoverin family of neuronal calcium sensors. The protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RCV1
Protein Interaction Partner: GIT2, TGFBR2, SMAD3, IL15RA, TOP1, PQBP1, CAV1, GRK5, GRK6, GRK1, ADRBK1,
Protein Size: 200 -
Molecular Weight
- 23 kDa
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Gene ID
- 5957
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NCBI Accession
- NM_002903, NP_002894
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UniProt
- P35243
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
Target
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