KDM2B antibody (Middle Region)

Catalog No. ABIN2778398

Product Details anti-KDM2B Antibody

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Dog, Rat, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM2B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LSFFKRCGNI CHIDLRYCKQ VTKEGCEQFI AEMSVSVQFG QVEEKLLQKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against FBXL10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXL10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1336 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KDM2B

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Alternative Name: FBXL10 (KDM2B Products)

Background: FBXL10 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which fun
Alias Symbols: CXXC2, Fbl10, JHDM1B, KDM2B, PCCX2, FBXL10
Protein Interaction Partner: RNF2, RYBP, SKP1, PCGF1, UBE2D1, KDM2B, HIST1H3A, KIAA0368, PCGF3, YAF2, SIN3A, CUL1, JUN, SUMO2, UBC, LZTR1, CEBPE, EZH2, BCOR,
Protein Size: 1336

Molecular Weight: 152 kDa

Gene ID: 84678

NCBI Accession: NM_032590, NP_115979

UniProt: Q8NHM5

Pathways: Tube Formation, Warburg Effect