CARS antibody (N-Term)

Catalog No. ABIN2778726

This anti-CARS antibody is a Rabbit Polyclonal antibody detecting CARS in WB. Suitable for Human, Mouse, Rat, Rabbit, Dog, Horse and Guinea Pig.

Quick Overview for CARS antibody (N-Term) (ABIN2778726)

Target: CARS (Cysteinyl-tRNA Synthetase (CARS))

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CARS Antibody

Binding Specificity: N-Term

Sequence: ADSSGQQAPD YRSILSISDE AARAQALNEH LSTRSYVQGY SLSQADVDAF

Predicted Reactivity: Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CARS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CARS

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CARS

Target: CARS (Cysteinyl-tRNA Synthetase (CARS))

Alternative Name: CARS

Background: CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. CARS gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Protein Interaction Partner: UBC, DNM1L, CAND1, LUC7L2, THUMPD3, JMJD6, XPO7, FAF1, SEC23A, SEC24D, HIRIP3, HIST1H4A, TTC1, TROVE2, SHMT1, PPM1G, PPAT, PAWR, KARS, IDE, HSPA4, GFPT1, GART, GARS, APEH, APP, SUMO2, PACSIN1, PACSIN3, PACSIN2, PSTPIP1, EEF1G,
Protein Size: 831

Molecular Weight: 95 kDa

Gene ID: 833