SERBP1 antibody (Middle Region)

Catalog No. ABIN2778739

The Rabbit Polyclonal anti-SERBP1 antibody has been validated for WB. It is suitable to detect SERBP1 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for SERBP1 antibody (Middle Region) (ABIN2778739)

Target: SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SERBP1 Antibody

Binding Specificity: Middle Region

Sequence: SYNYSDLDQS NVTEETPEGE EHHPVADTEN KENEVEEVKE EGPKEMTLDE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against SERBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SERBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 408 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SERBP1

Target: SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))

Alternative Name: SERBP1

Background: SERBP1 may play a role in the regulation of mRNA stability. It binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.
Alias Symbols: CGI-55, CHD3IP, DKFZp564M2423, FLJ90489, HABP4L, PAI-RBP1, PAIRBP1
Protein Interaction Partner: SERBP1, HUWE1, FUS, UBC, SUMO1, NEDD8, EIF2A, PRMT8, TSR1, DYNC1LI1, DYNC1I2, DYNC1H1, DYNLT3, RPS29, RPS26, RPS25, RPS24, RPS23, RPS20, RPS19, RPS14, RPS10, RPS6, RPS3, PARK2, UPF2, TARDBP, FBXO25, UBD, TERT, CD81, PAN2, MAP1LC3A, CSNK2A1, CTNNB1, MDC1,
Protein Size: 408

Molecular Weight: 45 kDa

Gene ID: 26135

NCBI Accession: NM_001018067, NP_001018077

UniProt: Q8NC51