CELF1 antibody (Middle Region)

Catalog No. ABIN2778749

The Rabbit Polyclonal anti-CELF1 antibody has been validated for WB and IHC. It is suitable to detect CELF1 in samples from Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Rabbit, Dog, Guinea Pig and Horse.

Quick Overview for CELF1 antibody (Middle Region) (ABIN2778749)

Target: CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CELF1 Antibody

Binding Specificity: Middle Region

Sequence: QMKPADSEKN NVEDRKLFIG MISKKCTEND IRVMFSSFGQ IEECRILRGP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CUGBP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CUGBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 512 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CELF1

Target: CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))

Alternative Name: CUGBP1

Background: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene.
Alias Symbols: BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50
Protein Interaction Partner: UBC, MDM2, RPA3, RPA2, RPA1, BMI1, TARDBP, RALY, HNRNPC, APP, ELAVL1, SUMO2, USP10, FUBP1, PPBP, DMPK, TOM1L1, CELF1,
Protein Size: 512

Molecular Weight: 56 kDa

Gene ID: 10658

NCBI Accession: NM_001172639, NP_001166110

Pathways: Ribonucleoprotein Complex Subunit Organization