HNRNPC antibody (C-Term)

Catalog No. ABIN2778889

This Rabbit Polyclonal antibody specifically detects HNRNPC in WB. It exhibits reactivity toward Human, Rat, Mouse, Rabbit, Cow, Dog, Pig, Horse, Goat, Guinea Pig and Saccharomyces cerevisiae.

Quick Overview for HNRNPC antibody (C-Term) (ABIN2778889)

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Pig, Horse, Goat, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HNRNPC Antibody

Binding Specificity: C-Term

Sequence: KMESEAGADD SAEEGDLLDD DDNEDRGDDQ LELKDDEKEP EEGEDDRDSA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%

Characteristics: This is a rabbit polyclonal antibody against Hnrnpc. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 313 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Alternative Name: Hnrnpc

Background: Hnrnpc binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. Hnrnpc may play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Hnrnpc interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.
Alias Symbols: AL022939, D14Wsu171e, Hnrpc, Hnrpc1, Hnrpc2, hnRNPC1, hnRNPC2, hnrnp-C
Protein Interaction Partner: Eed, Plcb1, Nap1l2,
Protein Size: 313

Molecular Weight: 34 kDa

Gene ID: 15381

NCBI Accession: NM_016884, NP_058580

UniProt: Q9Z204