SYNCRIP antibody (N-Term)

Catalog No. ABIN2778978

This Rabbit Polyclonal antibody specifically detects SYNCRIP in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig and Horse.

Quick Overview for SYNCRIP antibody (N-Term) (ABIN2778978)

Target: SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNCRIP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SYNCRIP Antibody

Binding Specificity: N-Term

Sequence: MATEHVNGNG TEEPMDTTSA VIHSENFQTL LDAGLPQKVA EKLDEIYVAG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SYNCRIP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SYNCRIP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 623 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SYNCRIP

Target: SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))

Alternative Name: SYNCRIP

Background: Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. SYNCRIP may be involved in translationally coupled mRNA turnover. It implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. It interacts in vitro preferentially with poly(A) and poly(U) RNA sequences.
Alias Symbols: PP68, NSAP1, GRYRBP, HNRPQ1, GRY-RBP, hnRNP-Q
Protein Interaction Partner: FUS, PRMT8, UBC, SPRTN, SUMO2, SUMO3, STAU1, MDM2, RPA3, RPA2, RPA1, RNF2, EED, rev, GNB2L1, IQGAP1, RPS21, RPL24, RPL23A, PSMD7, RPSA, IARS, PRMT1, HNRNPU, FKBP3, MAP1S, C14orf166, RPS27L, NELFB, PARK2, FBXO6, TARDBP, CSF2, CD81, IGSF8, HMGA2, ICAM1, HMG
Protein Size: 623

Molecular Weight: 69 kDa

Gene ID: 10492

NCBI Accession: NM_006372, NP_006363

UniProt: O60506