XPOT antibody (Middle Region)

Catalog No. ABIN2779026

This anti-XPOT antibody is a Rabbit Polyclonal antibody detecting XPOT in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for XPOT antibody (Middle Region) (ABIN2779026)

Target: XPOT (Exportin, tRNA (Nuclear Export Receptor For TRNAs) (XPOT))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XPOT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-XPOT Antibody

Binding Specificity: Middle Region

Sequence: TVLSDQQKAN VEAIMLAVMK KLTYDEEYNF ENEGEDEAMF VEYRKQLKLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 75%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against XPOT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human XPOT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 962 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for XPOT

Target: XPOT (Exportin, tRNA (Nuclear Export Receptor For TRNAs) (XPOT))

Alternative Name: XPOT

Background: XPOT belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.
Alias Symbols: XPO3
Protein Interaction Partner: SUMO2, SUMO3, UBC, RNF2, MCMBP, PAPSS1, NFRKB, APEX1, FBXO6, EGFR, IQCB1, CA9, ECT2, TXNL1, USP7, UBD, RAN, CUL5, FBXO25, SIRT7, EBNA-LP, HDAC5, MYC, CAMKK2, CLN3, AIRE, XPO7, NUP153, RANBP2, HDLBP, NUP214,
Protein Size: 962

Molecular Weight: 110 kDa

Gene ID: 11260

NCBI Accession: NM_007235, NP_009166

UniProt: O43592