EYA3 antibody (N-Term)

Catalog No. ABIN2779570

Product Details anti-EYA3 Antibody

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Horse, Sheep, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EYA3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KMQESGEQTI SQVSNPDVSD QKPETSSLAS NLPMSEEIMT CTDYIPRSSN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against EYA3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human EYA3

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EYA3

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Alternative Name: EYA3 (EYA3 Products)

Background: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.
Protein Size: 362

Molecular Weight: 39 kDa

Gene ID: 2140

NCBI Accession: NM_001282560, NP_001269489

UniProt: Q99504

Pathways: Positive Regulation of Response to DNA Damage Stimulus