PSMD6 antibody (N-Term)

Catalog No. ABIN2779618

The Rabbit Polyclonal anti-PSMD6 antibody has been validated for WB. It is suitable to detect PSMD6 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for PSMD6 antibody (N-Term) (ABIN2779618)

Target: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSMD6 Antibody

Binding Specificity: N-Term

Sequence: PLENLEEEGL PKNPDLRIAQ LRFLLSLPEH RGDAAVRDEL MAAVRDNNMA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PSMD6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 389 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PSMD6 antibody (ABIN2779618)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for PSMD6

Target: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Alternative Name: PSMD6

Background: PSMD6 acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Alias Symbols: KIAA0107, S10, SGA-113M, p44S10, Rpn7
Protein Interaction Partner: UBQLN1, HUWE1, UBC, SUMO2, PSMD14, TP53, SHFM1, PARK2, RNF11, NOS2, PSMD13, PSMD12, PSMD11, PSMD8, PSMD7, PSMD3, PSMD2, PSMD1, PSMC5, PSMC4, PSMC2, PSMD4, PSMC6, PSMC3, PSMC1, PSMB10, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, P
Protein Size: 389

Molecular Weight: 45 kDa

Gene ID: 9861

NCBI Accession: NM_014814, NP_055629

UniProt: Q15008

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway