SIRT6 antibody (N-Term)

Catalog No. ABIN2779625

This Rabbit Polyclonal antibody specifically detects SIRT6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Pig, Guinea Pig and Horse.

Quick Overview for SIRT6 antibody (N-Term) (ABIN2779625)

Target: SIRT6 (Sirtuin 6 (SIRT6))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIRT6 Antibody

Binding Specificity: N-Term

Sequence: STASGIPDFR GPHGVWTMEE RGLAPKFDTT FESARPTQTH MALVQLERVG

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SIRT6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 355 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SIRT6

Target: SIRT6 (Sirtuin 6 (SIRT6))

Alternative Name: SIRT6

Background: SIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by SIRT6 is included in class IV of the sirtuin family.
Alias Symbols: SIR2L6
Protein Interaction Partner: UBC, MDM2, AKT1, STUB1, SKP2, ABCF2, FAF1, VIM, UBE2D1, CHD3, NR0B2, tat, CCNDBP1, RELA, XRCC5, PRKDC, XRCC6, ELF5,
Protein Size: 355

Molecular Weight: 39 kDa

Gene ID: 51548

NCBI Accession: NM_016539, NP_057623

UniProt: Q8N6T7