PCBD1 antibody (C-Term)

Catalog No. ABIN2779651

Product Details anti-PCBD1 Antibody

Target: PCBD1 (Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCBD1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VALQAEKLDH HPEWFNVYNK VHITLSTHEC AGLSERDINL ASFIEQVAVS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against Pcbd1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 104 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCBD1

Target: PCBD1 (Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1))

Alternative Name: Pcbd1 (PCBD1 Products)

Background: Pcbd1 is involved in tetrahydrobiopterin biosynthesis. It seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. It is a coactivator for HNF1A-dependent transcription. It regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity.
Alias Symbols: Dcoh, Pcbd
Protein Interaction Partner: Pcbd2, Hnf1a, Zdhhc13, Pawr, Tle6, Chd4, Asb15, Brpf1, Cers2, Ercc8, Asb3, Zfp110, Hnf1b, Srebf1, Polr1a, Pcbd1, Zfp36l1, Bard1,
Protein Size: 104

Molecular Weight: 12 kDa

Gene ID: 13180

NCBI Accession: NM_025273, NP_079549

UniProt: P61458