HINFP antibody (Middle Region)
Quick Overview for HINFP antibody (Middle Region) (ABIN2779711)
Target
See all HINFP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- FKDRSKLREH LRSHTQEKVV ACPTCGGMFA NNTKFLDHIR RQTSLDQQHF
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Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Characteristics
- This is a rabbit polyclonal antibody against MIZF. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MIZF
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 517 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HINFP (Histone H4 Transcription Factor (HINFP))
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Alternative Name
- MIZF
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Background
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MIZF interacts with methyl-CpG-binding protein-2 (MBD2, MIM 603547), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression.MIZF interacts with methyl-CpG-binding protein-2 (MBD2, MIM 603547), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-62 BF726036.1 1-62 63-1549 BC017234.2 47-1533 1550-2058 AK056362.1 1518-2026 2059-2202 BC001073.2 2085-2228
Alias Symbols: DKFZP434F162, HiNF-P, ZNF743, MIZF
Protein Interaction Partner: POM121C, CDYL2, RBM17, RPUSD4, THAP7, RBM26, MIF4GD, NPDC1, TRIM44, ELP4, NIPBL, SRRM2, PRRC2C, MORF4L1, ZNHIT1, MDC1, EFTUD2, TTF2, U2AF1, TLE3, TRA2B, MKI67, JUND, GSPT1, ATN1, SREBF2, NPAT, MBD2, TRAF2, HDAC1, DHX9,
Protein Size: 517 -
Molecular Weight
- 60 kDa
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Gene ID
- 25988
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NCBI Accession
- NM_198971, NP_945322
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UniProt
- Q9BQA5
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Pathways
- Chromatin Binding
Target
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