Ataxin 2 antibody (Middle Region)

Catalog No. ABIN2780458

The Rabbit Polyclonal anti-Ataxin 2 antibody has been validated for WB and IHC. It is suitable to detect Ataxin 2 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig and Rabbit.

Quick Overview for Ataxin 2 antibody (Middle Region) (ABIN2780458)

Target: Ataxin 2 (ATXN2)

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Ataxin 2 Antibody

Binding Specificity: Middle Region

Sequence: HAPMMLMTTQ PPGGPQAALA QSALQPIPVS TTAHFPYMTH PSVQAHHQQQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ATXN2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATXN2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1313 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Ataxin 2

Target: Ataxin 2 (ATXN2)

Alternative Name: ATXN2

Background: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA ty
Alias Symbols: ATX2, FLJ46772, SCA2, TNRC13
Protein Interaction Partner: UBC, SUMO1, NEDD8, DDX6, WWOX, SH3GL3, SH3GL2, SHFM1, BMI1, PABPC1, Dlg4, MDC1, GPKOW, CCT5, SUMO2, PARK2, GOLGA6L5P, RBFOX1, ZNRD1, KIAA1279, TDRD7, GFI1B, NCOA4, BAG6, ATXN1, IDH3B, ACTN2, ACTN1, CAND1, CUL3, ISG15, SH3KBP1, TSG101, EGFR, CHGB, BIN1, PL
Protein Size: 1313

Molecular Weight: 140 kDa

Gene ID: 6311

NCBI Accession: NM_002973, NP_002964

UniProt: Q99700

Pathways: Ribonucleoprotein Complex Subunit Organization