TFAP2C antibody (N-Term)

Catalog No. ABIN2780497

This anti-TFAP2C antibody is a Rabbit Polyclonal antibody detecting TFAP2C in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Rabbit, Pig, Guinea Pig and Horse.

Quick Overview for TFAP2C antibody (N-Term) (ABIN2780497)

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Rabbit, Pig, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAP2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TFAP2C Antibody

Binding Specificity: N-Term

Sequence: MLWKITDNVK YEEDCEDRHD GSSNGNPRVP HLSSAGQHLY SPAPPLSHTG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TFAP2C. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TFAP2C

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 450 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFAP2C

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Alternative Name: TFAP2C

Background: TFAP2C is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.
Alias Symbols: AP2-GAMMA, ERF1, TFAP2G, hAP-2g
Protein Interaction Partner: ZFAND4, NR1I2, IKBKB, GPR22, CCNG1, KCTD1, SUMO1, UBE2I, BRCA1, HHV8GK18_gp81, KDM5B, MYC, ELAVL1, SUMO2, UBC, CITED4, CITED2, CITED1, TP53,
Protein Size: 450

Molecular Weight: 49 kDa

Gene ID: 7022

NCBI Accession: NM_003222, NP_003213

UniProt: Q92754

Pathways: Stem Cell Maintenance