YY1 antibody (N-Term)

Catalog No. ABIN2780503

The Rabbit Polyclonal anti-YY1 antibody has been validated for WB. It is suitable to detect YY1 in samples from Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Sheep, Pig and Horse.

Quick Overview for YY1 antibody (N-Term) (ABIN2780503)

Target: YY1 (YY1 Transcription Factor (YY1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Sheep, Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YY1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-YY1 Antibody

Binding Specificity: N-Term

Sequence: MASGDTLYIA TDGSEMPAEI VELHEIEVET IPVETIETTV VGEEEEEDDD

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 91%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against YY1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human YY1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 414 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for YY1

Target: YY1 (YY1 Transcription Factor (YY1))

Alternative Name: YY1

Background: YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
Alias Symbols: DELTA, NF-E1, UCRBP, INO80S, YIN-YANG-1
Protein Interaction Partner: HDAC1, SMURF2, UBC, SHFM1, RNF2, BMI1, SUZ12, RYBP, GABPB1, GABPA, PCGF2, RING1, EP300, LAMC2, SPRY1, SLC39A7, NR1H2, TESK1, RAF1, NFKB1, GRN, CRKL, ARRB1, SP1, WDHD1, ZNF24, NHP2L1, NCL, ZNF830, APP, ZNF638, EED, SMAD3, SMAD2, EZH2, SUMO1, SUMO3, INO80E,
Protein Size: 414

Molecular Weight: 45 kDa

Gene ID: 7528

NCBI Accession: NM_003403, NP_003394

UniProt: P25490