CIAO1 antibody (C-Term)

Catalog No. ABIN2780621

This Rabbit Polyclonal antibody specifically detects CIAO1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig and Rabbit.

Quick Overview for CIAO1 antibody (C-Term) (ABIN2780621)

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIAO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CIAO1 Antibody

Binding Specificity: C-Term

Sequence: HSRTIYDIAW CQLTGALATA CGDDAIRVFQ EDPNSDPQQP TFSLTAHLHQ

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against WDR39. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WDR39

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 339 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CIAO1

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Alternative Name: WDR39

Background: WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
Alias Symbols: CIA1, WDR39
Protein Interaction Partner: FAM96B, SF1, MEOX1, FAM96A, MMS19, FMNL2, TOE1, DPP9, FMNL3, CTU1, PPIL4, MAK16, WDR75, NSRP1, EEPD1, WDR61, CDC73, UPF3B, NARFL, YAE1D1, TYW1, ELP2, ELP3, UCKL1, CDKAL1, DPP8, ELP6, PAF1, PLEKHA5, PHAX, RTEL1, ELP4, POLA2, ELP5, WDR43, ERP29, GLRX3, CTR9
Protein Size: 339

Molecular Weight: 38 kDa

Gene ID: 9391

NCBI Accession: NM_004804, NP_004795

UniProt: O76071