MYB antibody (N-Term)

Catalog No. ABIN2780679

This Rabbit Polyclonal antibody specifically detects MYB in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for MYB antibody (N-Term) (ABIN2780679)

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MYB Antibody

Binding Specificity: N-Term

Sequence: YDGLLPKSGK RHLGKTRWTR EEDEKLKKLV EQNGTDDWKV IANYLPNRTD

Specificity: Based on the sequence of the immunizing peptide, this antibody is 100 % homologous to all 12 isoforms of hMYB.

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against MYB. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 323 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Alternative Name: MYB

Background: MYB may be a transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. It plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Alias Symbols: Cmyb, c-myb, c-myb_CDS, efg
Protein Interaction Partner: UBC, ERC2, UPF2, PPM1K, MYOZ2, SUMO1, SUMO2, CCND3, EP300, RBX1, FBXW5, PIAS1, CUL4A, UBE2I, DDB1, TRAF6, STAT5A, GATA3, KAT5, Fbxw7, CREBBP, LEF1, RPL4, KAT2B, CHD3, SIN3A, TRIM28, NCOR1, SKI, HIPK2, NLK, SP100, HLF, PARP1, ASH2L, RBBP5, KMT2A, MEN1, WDR
Protein Size: 323

Molecular Weight: 38 kDa

Gene ID: 4602

NCBI Accession: NM_001130172

UniProt: P10242

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process