SOX3 antibody (C-Term)

Catalog No. ABIN2780699

This anti-SOX3 antibody is a Rabbit Polyclonal antibody detecting SOX3 in WB. Suitable for Human, Mouse, Rat, Dog, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for SOX3 antibody (C-Term) (ABIN2780699)

Target: SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOX3 Antibody

Binding Specificity: C-Term

Sequence: QRACLGDLRD MISMYLPPGG DAADAASPLP GGRLHGVHQH YQGAGTAVNG

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 77%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against SOX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SOX3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 446 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOX3

Target: SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

Alternative Name: SOX3

Background: SOX3 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.
Alias Symbols: PHP, GHDX, MRGH, PHPX, SOXB
Protein Interaction Partner: TRRAP, SUMO1, SUMO2, PAX6,
Protein Size: 446

Molecular Weight: 45 kDa

Gene ID: 6658

NCBI Accession: NM_005634, NP_005625

UniProt: P41225