NEUROD2 antibody (C-Term)

Catalog No. ABIN2780746

The Rabbit Polyclonal anti-NEUROD2 antibody has been validated for WB. It is suitable to detect NEUROD2 in samples from Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig and Rabbit.

Quick Overview for NEUROD2 antibody (C-Term) (ABIN2780746)

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEUROD2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NEUROD2 Antibody

Binding Specificity: C-Term

Sequence: PGSRPTGHGL VFGSSAVRGG VHSENLLSYD MHLHHDRGPM YEELNAFFHN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NEUROD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NEUROD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 382 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NEUROD2

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Alternative Name: NEUROD2

Background: NEUROD2 is a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of NEUROD2 can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. NEUROD2 can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.
Alias Symbols: NDRF, bHLHa1
Protein Interaction Partner: TK1, PKN1,
Protein Size: 382

Molecular Weight: 41 kDa

Gene ID: 4761

NCBI Accession: NM_006160, NP_006151

UniProt: Q15784